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Literature summary extracted from

  • Zhang, C.; Zhu, Y.; Rui, W.; Dai, J.; Shen, Z.
    Expression of kallikrein-related peptidase 7 is decreased in prostate cancer (2015), Asian J. Androl., 17, 106-110 .
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
3.4.21.117 medicine study on KLK7 expression in prostate cancer. A total of 64 of 92 (69.57%) benign cases show positive staining for KLK7 and 23 of 116 (19.83%)malignant cases show positive staining. The expression level of kallikrein-related peptidase 7 mRNA is significantly decreased in prostate cancer tissues compared with that in benign prostate hyperplasia tissues and normal prostate tissue. The protein expression levels of KLK7 is lower in prostate cancer than in benign prostate hyperplasia tissues and normal prostate tissue. Kallikrein-related peptidase 7 and KLK7 expression are downregulated in prostate cancer and lower expression of kallikrein-related peptidase 7 closely correlates with higher Gleason score and higher prostate-specific antigen level Homo sapiens

Organism

EC Number Organism UniProt Comment Textmining
3.4.21.117 Homo sapiens P49862
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Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.21.117 prostate cancer cell line
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 Homo sapiens
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3.4.21.117 prostate gland
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 Homo sapiens
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